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Description:

The Cytomegalie-Virus (CMV) Antibodies test is designed to detect an often-unobvious CMV infection.

 

Cytomegalovirus infection (CMV) is a viral infection that rarely causes obvious illness. The virus that causes CMV is part of the herpes virus family and, like other herpes viruses, may become dormant for a period of time and then be reactivated. CMV mainly affects young children but it is estimated that, by age 30 in the United States, half of all adults are, or have been, infected. The virus can pass from an infected, pregnant mother to her child through the shared blood supply (umbilical cord).

 

Physicians recognize three clinical forms of CMV. These include: (1) CMV inclusion disease of the newborn, which ranges in severity from being without symptoms to being a severe disease affecting the liver, spleen and central nervous system, resulting in possible developmental disabilities; (2) Acute acquired CMV infection, which is similar to infectious mononucleosis and characterized by fever, malaise, skeletal-muscular pain, and the absence of a sore throat; (3) CMV in immuno-compromised persons (for instance, people who have had organ transplants or who have HIV) with increased risk for difficult eye infections (CMV retinitis), gastrointestinal CMV, and encephalitis.

 

Antibodies test:

After a person is infected with Borrelia burgdorferi, the bacterium that causes most cases of Lyme disease, their immune system will recognize the infection and react by producing antibodies against the bacterium. This is usually a two-step process. IgM antibodies are the first wave of attack. They appear within 3-4 weeks after initial infection and hit peak concentrations in about 6-8 weeks. IgM antibodies can persist for several months before they are no longer detectable.

 

The second phase of response is the production of IgG antibodies. They appear 6-8 weeks after infection and hit their peak concentrations at 4-6 months. Once infected, a person’s IgG level may remain detectable for the rest of his/her life. The spirochetes are tissue-loving organisms; therefore, their presence is transient in blood and other body fluids. One of the most important factors in laboratory tests for Lyme disease is timing the collection of the samples. If you obtain the sample too early or the patient doesn’t have a strong enough immune response, you may get a false negative test result.

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